Characteristics and functions of the four MS (mechanosensitive) channels, MscL, MscS, TREK-1, and Piezo involved in mechanosensation in bacteria and mammals

Range Table - link
Organism Various
Reference Peyronnet R, Tran D, Girault T, Frachisse JM. Mechanosensitive channels: feeling tension in a world under pressure. Front Plant Sci. 2014 Oct 21 5: 558. doi: 10.3389/fpls.2014.00558. p.3 table 1PubMed ID25374575
Primary Source See refs beneath table
Comments P.4 left column 2nd paragraph: "Several structure function studies also provided crucial information for a better understanding of the gating of these channels and together these approaches contribute to make TREK, one of the most studied MS channels with the bacterial MscS and MscL. Apart from the bilayer itself, TREK-1 activity is regulated by a plethora of stimuli (Table 1)." P.4 left column 4th paragraph: "Piezo protein (from the Greek “p´ιesi” meaning pressure) discovered by (primary source) Coste et al. (2010) was shown to be an essential component of a cationic non-selective MS channel from mouse neuroblastoma cells (Table 1)."
Entered by Uri M
ID 112699