Mean information content (bits of information) in transcription factor sequence

Range Table - link bits of information
Organism Various
Reference Wunderlich Z, Mirny LA. Different gene regulation strategies revealed by analysis of binding motifs. Trends Genet. 2009 Oct25(10):434-40. supplementary material p.15 table S6PubMed ID19815308
Primary Source See refs beneath table
Method Supplementary material p.1 top paragraph:"Binding motifs were accessed from the references noted in Table S6. In some cases, RegTransBase contains several versions of motifs for the same TF [Transcription Factor]. If several motifs were present for a TF, the motif built using maximal number of cognate sites was selected. Background nucleotide frequencies were calculated for those organisms with completed genome sequences and average background frequencies were used for all others."
Comments P.437 left column top paragraph:"Taken together, [investigators] conclude the biases from the number of sites used to construct a TF-binding motif do not change [their] general findings. Finally, these results are consistent for motifs obtained both in vivo and in vitro and for all available data sets (Table S6 in the supplementary material)." For properties of binding motifs for bacteria, yeast and multicellular eukaryotes see p.436 figure 2 (refs beneath figure) link
Entered by Uri M
ID 111567