Membrane turnover rate in hairy cell leukemia (HCL) cell

Value 6 hours
Organism Human Homo sapiens
Reference Burns GF, Baker CR, Cawley JC, Hayhoe FG. The rate of membrane turnover by the hairy cells of leukemic reticuloendotheliosis: a kinetic study of a receptor for IgM. J Immunol. 1977 Oct119(4):1279-84. p. 1281 bottom of pagePubMed ID894034
Method Researchers studied the kinetics of re-expression of a recently described receptor for IgM on the HC (hairy cell) of HCL and the lymphocytes of CLL (refs 21, 26 in article). It is demonstrated that the kinetics of EA (IgM) rosette formation and re-expression by HC follow a cyclical pattern with a modal peak-to-peak re-expression time of 6 hr.
Comments See BNID 105559, 105561, 105562
Entered by Uri M
ID 105560