| Value |
40
µm^2/sec
|
| Organism |
Rat Rattus norvegicus |
| Reference |
Lukacs GL, Haggie P, Seksek O, Lechardeur D, Freedman N, Verkman AS. Size-dependent DNA mobility in cytoplasm and nucleus. J Biol Chem. 2000 Jan 21 275(3):1625-9. p.1628 right column 2nd paragraphPubMed ID10636854
|
| Primary Source |
Politz JC, Browne ES, Wolf DE, Pederson T. Intranuclear diffusion and hybridization state of oligonucleotides measured by fluorescence correlation spectroscopy in living cells. Proc Natl Acad Sci U S A. 1998 May 26 95(11):6043-8.PubMed ID9600914
|
| Method |
(Primary source:) Fluorescence correlation spectroscopy |
| Comments |
Although the majority of oligo(dT) was immobile,
probably because of hybridization to poly(A) sequences, a
significant fraction of the poly(dT) was free with an apparent
diffusion coefficient of 4^10^-7 cm2/s, nearly the same as that
measured in aqueous solutions. |
| Entered by |
Uri M |
| ID |
106084 |