Number of replication origin sites in OriDB database

Value 613 Replication origin sites Range: 279 Confirmed: 192 Likely: 142 Dubious Replication origin sites
Organism Budding yeast Saccharomyces cerevisiae
Reference Nieduszynski CA, Hiraga S, Ak P, Benham CJ, Donaldson AD. OriDB: a DNA replication origin database. Nucleic Acids Res. 2007 Jan35(Database issue):D40-6 p.D42 left column 2nd paragraphPubMed ID17065467
Method P.D41 right column 3rd paragraph: "Most of the information in the OriDB database is collated from four microarray-based studies, each of which produced a list of proposed origin sites (refs 24–27), and a fifth study which produced a list of confirmed origin sites (ref 12)."
Comments P.D42 left column top paragraph: "‘Confirmed’ origins are those have been cloned and tested by ARS [Autonomously Replicating Sequences] assay and/or have been detected by 2D gel analysis. ‘Likely’ origin sites have been identified by two (or more) microarray studies but have not yet been confirmed. ‘Dubious’ origin sites are those identified by only one microarray study." P.D42 left column 2nd paragraph: "Data from additional studies will be added to the database as they become available. This process may result in the criteria described above ‘evolving’. The status of predicted origins will certainly change as more origin sites are experimentally verified. At the time of writing OriDB contains 613 replication origin sites (279 Confirmed 192 Likely and 142 Dubious)." Database site address - link
Entered by Uri M
ID 107654