Length of chromosomal origin of replication

Range ~200 base pairs
Organism Budding yeast Saccharomyces cerevisiae
Reference Raghuraman et al., Replication dynamics of the yeast genome. Science. 2001 Oct 5 294(5540):115-21. DOI: 10.1126/science.294.5540.115 p.115 right columnPubMed ID11588253
Method Abstract:"Oligonucleotide microarrays were used to map the detailed topography of chromosome replication in the budding yeast Saccharomyces cerevisiae."
Comments p.115 right column:"There are estimated to be ~200 to 400 ARSs [Autonomous Replication Sequence elements] in the yeast genome (BNID 111672), and most, but not all, function as chromosomal origins (ref 3). The few origins investigated at the sequence level usually encompass ~200 base pairs (bp), most contain a perfect match or a one-base mismatch to an 11-bp ARS consensus sequence (ACS) (refs 4, 5)."
Entered by Uri M
ID 111673