Length of essential A•T origin of replication sequence

Value 11 bp
Organism Budding yeast Saccharomyces cerevisiae
Reference Benjamin Lewin, Genes VIII 2004, p.359 "key concepts" text box
Comments An ARS (autonomously replicating sequence) extends for ~50 bp and includes a consensus sequence (A) and additional elements (B1-B3). See BNID 102577 Note-Méchali 2010 PMID 20861881 p.728 right column bottom paragraph:"Saccharomyces cerevisiae ORCs specifically recognize a 12 bp consensus sequence (ref 4), but Schizosaccharomyces pombe and metazoan ORCs do not exhibit sequence specificity (refs 5,6)."
Entered by Uri M
ID 106930