| Comments |
"For [researchers'] corrected data, the median number of proteins translated per mRNA is 9,800
compared to Schwanhausser et al.'s (2011) original estimate of 900 and their second
estimate of 2,800. In yeast, the ratio of protein molecules translated per mRNA is
4,200-5,600 (Ghaemmaghami et al., 2003 Lu et al., 2007 BNID 104745, 104185). Given that mammalian cells
have a higher protein copy number than yeast (Milo et al., 2010), it is not unreasonable
that the ratio in mammalian cells would be higher." |