Direct sequencing estimates of mutation rate

Value 3.3E-10 mutations/site/generation Range: Table - link mutations/site/generation
Organism Budding yeast Saccharomyces cerevisiae
Reference Kondrashov FA, Kondrashov AS. Measurements of spontaneous rates of mutations in the recent past and the near future. Philos Trans R Soc Lond B Biol Sci. 2010 Apr 27 365(1544):1169-76. doi: 10.1098/rstb.2009.0286. p.1172 table 1PubMed ID20308091
Primary Source Lynch, M. et al. 2008 A genome-wide view of the spectrum of spontaneous mutations in yeast. Proc. Natl Acad. Sci. USA 105, 9272–9277. (doi:10.1073/pnas. 0803466105)PubMed ID18583475
Method "As far as quantitative estimates of mutation rate are concerned, a large fraction of them have been obtained in recent studies that use a multigeneration direct sequencing approach (table 1)."
Comments See "comments" column.
Entered by Uri M
ID 109998