Direct sequencing estimates of mutation rates in mitochondrion (point mutations)
| Value | 6.2E-08 mutations/site/generation Range: Table - link mutations/site/generation |
|---|---|
| Organism | Fruit fly Drosophila melanogaster |
| Reference | Kondrashov FA, Kondrashov AS. Measurements of spontaneous rates of mutations in the recent past and the near future. Philos Trans R Soc Lond B Biol Sci. 2010 Apr 27 365(1544):1169-76. doi: 10.1098/rstb.2009.0286. p.1172 table 1PubMed ID20308091 |
| Primary Source | Haag-Liautard, C., Coffey, N., Houle, D., Lynch, M., Charlesworth, B. & Keightley, P. D. 2008 Direct estimation of the mitochondrial DNA mutation rate in Drosophila melanogaster. PLoS Biol. 6, e204. (doi:10. 1371/journal.pbio.0060204)PubMed ID18715119 |
| Method | "As far as quantitative estimates of mutation rate are concerned, a large fraction of them have been obtained in recent studies that use a multigeneration direct sequencing approach (table 1)." |
| Comments | See "comments" column. |
| Entered by | Uri M |
| ID | 109993 |