| Value |
2.6
nm
|
| Organism |
Human Homo sapiens |
| Reference |
Mohr D, Frey S, Fischer T, Güttler T, Görlich D. Characterisation of the passive permeability barrier of nuclear pore complexes. EMBO J. 2009 Sep 2 28(17):2541-53.PubMed ID19680228
|
| Method |
In this study researchers used a size series of 11 inert permeation probes with masses between 0.6 and 40 kDa to explore the permeability barrier of NPCs. The data obtained suggest a sieve-like barrier with a heterogeneous mesh size and a prevalent mesh radius of ˜2.6 nm. Researchers used permeabilized HeLa cells. |
| Comments |
This is far more narrow than the earlier assumed 4.5 nm (Paine et al, 1975 Keminer and Peters, 1999 BNID 104250). |
| Entered by |
Uri M |
| ID |
105654 |