Weight of prostate at different ages

Range 40-49year old (yo) 28.2g: 50-59yo 30.8g: 60-70yo 35g: older than 75yo 46.2 grams
Organism Human Homo sapiens
Reference Tomasetti C, Li L, Vogelstein B. Stem cell divisions, somatic mutations, cancer etiology, and cancer prevention. Science. 2017 Mar 24 355(6331):1330-1334. doi: 10.1126/science.aaf9011 Supplementary Materials p.3 6th paragraphPubMed ID28336671
Primary Source [43] Zhang SJ et al., Relationship between age and prostate size. Asian J Androl. 2013 Jan15(1):116-20. doi: 10.1038/aja.2012.127 [44] Bosch JL, Tilling K, Bohnen AM, Bangma CH, Donovan JL. Establishing normal reference ranges for prostate volume change with age in the population-based Krimpen-study: prediction of future prostate volume in individual men. Prostate. 2007 Dec 1 67(16):1816-24 DOI: 10.1002/pros.20663PubMed ID23223031, 17935157
Method Primary source [43] abstract: "One thousand male volunteers were randomly recruited from the Shanghai community, and the length, width, height, volume of the transition zone (TZ) and the whole prostates were measured by transrectal ultrasound (TRUS). Each volunteer was evaluated by the International Prostate Symptom Score (IPSS)." Primary source [44] abstract: "In a community-based study, prostate volume was determined at baseline and after 2.1 and 4.2 years in men without prostate cancer. A bivariate multilevel growth curve model was used to estimate the pattern of change of prostate volume with age."
Comments Supplementary Materials p.3 6th paragraph: "The human prostate has a weight that increases with age: 28.2 g in 40-49 year old individuals, 30.8 g in 50-59 year old individuals, 35 g in 60-70 year old individuals (primary source 43), and 46.2 g in those older than 75 years (primary source 44)."
Entered by Uri M
ID 115555