Number of primordial follicles a female has

Range ~5e+6 at birth: ~5e+5 at menarche: ~25,000 at age 37: 1,000 at menopause %
Organism Human Homo sapiens
Reference George K, Kamath MS. Fertility and age. J Hum Reprod Sci. 2010 Sep3(3):121-3. Introduction, 1st paragraphPubMed ID21234171
Primary Source Faddy MJ, Gosden RG, Gougeon A, Richardson SJ, Nelson JF. Accelerated disappearance of ovarian follicles in mid-life: implications for forecasting menopause. Hum Reprod. 1992 Nov7(10):1342-6.PubMed ID1291557
Comments Menarche is the first menstrual cycle. The ability to procreate is age related, more so in the female partner. In the female fetus, germ cell proliferation comes to a standstill by around 20 weeks, resulting in women being born with a set number of primordial follicles. At birth, the female child is born with about 5 million primordial follicles which decrease to about 500,000 at menarche. With each subsequent menstrual cycle follicular atresia/apoptosis continues with the numbers decreasing to about 25,000 at the age of 37 and 1000 close to menopause.
Entered by Uri M
ID 108081