| Range |
Table - link
|
| Organism |
Mammalian tissue culture cell |
| Reference |
Tsaneva-Atanasova K, Burgo A, Galli T, Holcman D. Quantifying neurite growth mediated by interactions among secretory vesicles, microtubules, and actin networks. Biophys J. 2009 Feb96(3):840-57. p. 844 table 1PubMed ID19186125
|
| Method |
Since researchers' model is based on physical properties of the cell, it
should, in principle, apply to a wide range of biological
systems where protrusions are formed in such a manner.
They have indeed applied this approach to neuronal genesis
and thus chosen parameter values within the range measured
in experimental studies of neuronal cultures or PC12 (rat adrenal medulla) cells. In
the case of microtubules assembly/disassembly rates,
however, such data is limited therefore, they have taken these
rates from in vitro studies with purified tubulin (Fygenson et al., 1994 PMID 9962129) |
| Comments |
Researchers have shown here that neurite initiation and growth are
based on complex interactions between vesicles, to deliver
membrane to the neurite microtubules, to stabilize the neurite
and guide the vesicles movement and the actin network
that controls the degree of interaction between the microtubules
and the neurite. |
| Entered by |
Uri M |
| ID |
105558 |