A simple energy budget for normal and ascites cancer cells

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Reference Zu XL, Guppy M. Cancer metabolism: facts, fantasy, and fiction. Biochem Biophys Res Commun. 2004 Jan 16 313(3):459-65. p.460 table 1PubMed ID14697210
Primary Source Guppy M, Leedman P, Zu X, Russell V. Contribution by different fuels and metabolic pathways to the total ATP turnover of proliferating MCF-7 breast cancer cells. Biochem J. 2002 May 15 364(Pt 1):309-15.PubMed ID11988105
Comments "Pioneering work on cancer metabolism was done by Warburg in 1929. These data were summarized by Warburg [PMID 13298683] and are shown in Table 1. Compared to liver and kidney cells of adult animals, mouse ascites cancer cells showed a dramatically increased contribution by glycolytic ATP turnover to total ATP production under air-saturated conditions."
Entered by Uri M
ID 110692