| Range |
neurons ~400: microglia ~10,000
|
| Organism |
European medicinal leech Hirudo medicinalis |
| Reference |
Biber K, Owens T, Boddeke E. What is microglia neurotoxicity (Not)? Glia. 2014 Jun62(6):841-54. doi: 10.1002/glia.22654 p.841 left columnPubMed ID24590682
|
| Primary Source |
Le Marrec-Croq F, Drago F, Vizioli J, Sautière PE, Lefebvre C. The leech nervous system: a valuable model to study the microglia involvement in regenerative processes. Clin Dev Immunol. 2013 2013: 274019. doi: 10.1155/2013/274019PubMed ID23878582
|
| Comments |
P.841 left column: "It is well known that microglia are present in the nervous systems of “primitive” organisms like the leech, snails, mussels, insects and crustaceans (Sonetti et al., 1994). In fact, microglia research was first started in the leech as Pio del Rio-Hortega obtained his first microglia stainings in Hirudu Medicinalis (see for review: Kettenmann et al., 2011, Sieger
and Peri, 2013). The nervous system of the leech is mainly composed of evenly distributed body ganglia. Each of these
body ganglia contains around 400 neurons and 10,000 microglia, thus in the leech microglia by far outnumber neurons (primary source)." |
| Entered by |
Uri M |
| ID |
114496 |