| Value |
9
µm/min
Range: ±6 µm/min
|
| Organism |
Human Homo sapiens |
| Reference |
Butler KL et al., Burn injury reduces neutrophil directional migration speed in microfluidic devices. PLoS One. 2010 Jul 30 5(7):e11921. doi: 10.1371/journal.pone.0011921. p.6 right column 2nd paragraphPubMed ID20689600
|
| Method |
Abstract:"...[investigators] developed a microfluidic device that is simple to operate and allows for precise and robust measurements of chemotaxis speed and persistence characteristics at single-cell resolution. Using this assay, [they] established a reference set of migration speed values for neutrophils from healthy subjects." |
| Comments |
P.6 right column 2nd paragraph:"Neutrophil motility was measured in a total of 24 samples from 2 pediatric and 6 adult patients (mean age 23 years, range 1–48 years) after sustaining 20–60% TBSA [total body surface area] burns (Table 1) 63% of patients were male, and 38% were female. The most common co-morbidities were depression and hypertension. No patient took immunosuppressant drugs. Across the entire data set, the average neutrophil migration speed in burn patients was 9±6 µm/min, significantly lower than in controls (p<0.01)." |
| Entered by |
Uri M |
| ID |
112248 |