| Value |
17
µm/min
Range: ±6 µm/min
|
| Organism |
Human Homo sapiens |
| Reference |
Butler KL et al., Burn injury reduces neutrophil directional migration speed in microfluidic devices. PLoS One. 2010 Jul 30 5(7):e11921. doi: 10.1371/journal.pone.0011921. p.5 right columnPubMed ID20689600
|
| Method |
Abstract:"...[investigators] developed a microfluidic device that is simple to operate and allows for precise and robust measurements of chemotaxis speed and persistence characteristics at single-cell resolution. Using this assay, [they] established a reference set of migration speed values for neutrophils from healthy subjects." |
| Comments |
P.5 left column:"In additional control experiments, in the absence of fMLP [N-Formylmethionyl-leucyl-phenylalanine] chemokine, neutrophils did not migrate through the side channels of the device. Furthermore, when a sample of neutrophils was diluted ten-fold, the measured average migration speed was unchanged (17±6 µm/min and 18±4 µm/min, p = 0.3), suggesting that migration speed was independent of the concentration of neutrophils in the device." |
| Entered by |
Uri M |
| ID |
112247 |