| Comments |
P.365 right column bottom paragraph:"In most living cells, the cytoplasmic G-actin concentration (~100 μM) is extraordinarily higher than the critical concentration (Cc) of actin filaments (~0.1μM) (Pollard et al., 2000 BNID 109811). This high G-actin concentration is maintained by F-actin disassembly by ADF/cofilin, and via the prevention of spontaneous G-actin nucleation by G-actin–sequestering proteins, profilin and thymosin-β4, and the blockage of F-actin polymerization by F-actin–capping proteins (Pantaloni and Carlier, 1993 Barkalow et al., 1996 Bamburg et al., 1999 Pollard et al., 2000)." |