Critical concentration for barbed-end polymerization (unspecified organism)

Range ~0.1 μM
Organism Eukaryotes
Reference Dominguez R, Holmes KC. Actin structure and function. Annu Rev Biophys. 2011 40 :169-86. doi: 10.1146/annurev-biophys-042910-155359. p.174 left column bottom paragraphPubMed ID21314430
Comments "Profilin (together with Tß4) contributes to maintaining a large fraction (~50%) of the cellular actin in the unpolymerized pool, at a concentration (~20–100 µM) that is 200- to 1000-fold higher than the critical concentration for barbed-end polymerization (~0.1 µM)."
Entered by Uri M
ID 109811