Value |
7
µm
|
Organism |
Mouse Mus musculus |
Reference |
Li L et al., Visualizing the distribution of synapses from individual neurons in the mouse brain. PLoS One. 2010 Jul 9 5(7):e11503. doi: 10.1371/journal.pone.0011503. p.7 right column top paragraphPubMed ID20634890
|
Primary Source |
Mukamel EA, Nimmerjahn A, Schnitzer MJ (2009) Automated analysis of cellular signals from large-scale calcium imaging data. Neuron 63: 747–760.PubMed ID19778505
|
Method |
Primary source abstract:"[Investigators] used automated procedures to analyze data recorded by two-photon Ca(2+) imaging in the cerebellar vermis of awake behaving mice." |
Comments |
p.6 left column bottom paragraph to right column top paragraph:"[Investigators’] finding [BNID 112026] implies that granule cells make denser connections in the molecular layer than previously thought. A recent study using calcium imaging suggests that the width of planar Purkinje cell dendritic tree is on average 7µm [primary source]. Given that each parallel fiber usually forms 1–2 synapses with a Purkinje cell [PMID 16759785], it is possible that a parallel fiber synapses with almost all Purkinje cells whose dendritic branches are within its reach." |
Entered by |
Uri M |
ID |
112027 |