Molecular mass of nuclear pore complex (NPC)

Range vertebrates ~125MDa: yeast ~66MDa MDa
Organism Eukaryotes
Reference Adam SA. The nuclear pore complex. Genome Biol. 2001 2(9):REVIEWS0007. p.1 left column bottom paragraphPubMed ID11574060
Primary Source [1] Reichelt R, Holzenburg A, Buhle EL, Jarnik M, Engel A, Aebi U: Correlation between structure and mass distribution of the nuclear pore complex and of distinct pore complex components. J Cell Biol 1990, 110: 883-894. [2] Rout MP, Blobel G: Isolation of the yeast nuclear pore complex. J Cell Biol 1993, 123: 771-783.PubMed ID2324201, 8227139
Comments "Nuclear pore complexes are proteinaceous structures embedded in the double membrane of the nuclear envelope. In order to understand how the NPC functions, it is useful to examine the similarities and differences between NPCs from the yeast Saccharomyces cerevisiae and the frog Xenopus laevis. The NPC is a large structure with a molecular weight of approximately 125 MDa in vertebrates and 66 MDa in yeast [primary sources]."
Entered by Uri M
ID 111129