Value |
1.2E-08
mutation/nucleotide/generation
|
Organism |
Human Homo sapiens |
Reference |
Kong et al., Rate of de novo mutations and the importance of father's age to disease risk. Nature. 2012 Aug 23 488(7412):471-5. doi: 10.1038/nature11396. abstractPubMed ID22914163
|
Method |
"[Researchers] conduct a study of genome-wide mutation rates by sequencing the entire genomes of 78 Icelandic parent-offspring trios at high coverage." |
Comments |
"[Researchers] show that in [their] samples, with an average father's age of 29.7, the average de novo mutation rate is 1.20?×?10(-8) per nucleotide per generation." |
Entered by |
Uri M |
ID |
110292 |