Ratio of new mutations passed on by fathers compared to mothers

Range ≈4 unitless
Organism Human Homo sapiens
Reference Callaway E. Fathers bequeath more mutations as they age. Nature. 2012 Aug 23 488(7412):439. doi: 10.1038/488439a. p.439 middle column top paragraphPubMed ID22914142
Primary Source Kong et al., Rate of de novo mutations and the importance of father's age to disease risk. Nature. 2012 Aug 23 488(7412):471-5. doi: 10.1038/nature11396.PubMed ID22914163
Method "Stefánsson [primary source], whose company maintains genetic information on most Icelanders, compared the whole-genome sequences of 78 trios of a mother, father and child. The team searched for mutations in the child that were not present in either parent and that must therefore have arisen spontaneously in the egg, sperm or embryo. [Primary source] reports the largest such study of nuclear families so far."
Comments "Fathers passed on nearly four times as many new mutations as mothers: on average, 55 versus 14."
Entered by Uri M
ID 110290