The contribution of different steps in gene expression to the variance in protein abundances between genes
Range | Table - link |
---|---|
Organism | Mammalian tissue culture cell |
Reference | Li et al. (2014), System wide analyses have underestimated protein abundances and the importance of transcription in mammals. PeerJ 2:e270 DOI 10.7717/peerj.270 p.10 table 1PubMed ID24688849 |
Method | "Western blot and SILAC mass spectrometry measurements" |
Comments | "In addition to determining protein and mRNA abundances, Schwanhausser et al. (2011) directly measured mRNA and protein degradation rates and calculated the percentage that each contributed to the variance in protein abundances. Using this information, it is possible to recalculate the relative importance of transcription, RNA degradation, translation and protein degradation for different scenarios (Table 1)." Note-four right-most columns add up to 100% in each row. |
Entered by | Uri M |
ID | 110237 |