Protein turnover in HeLa cell and C2C12 mouse cells
Range | Excel Table - link |
---|---|
Organism | Mammals |
Reference | Cambridge SB, Gnad F, Nguyen C, Bermejo JL, Krüger M, Mann M. Systems-wide proteomic analysis in mammalian cells reveals conserved, functional protein turnover. J Proteome Res. 2011 Dec 2 10(12):5275-84. doi: 10.1021/pr101183k. Suppl Table 1 (Excel)PubMed ID22050367 |
Method | Stable isotope labeling in cell culture (SILAC) |
Comments | "The majority of identified proteins displayed a slow to intermediate turnover and thus could be measured accurately. Overall, more than 99% of all proteins had a labeled versus unlabeled ratio of less than 10-fold (Supplementary Table 1, Supporting Information)." |
Entered by | Uri M |
ID | 109815 |