Activation energy of transport by ion channels
| Range | ~15 to 25 kJ/mol |
|---|---|
| Organism | Generic |
| Reference | Latorre R, Miller C. Conduction and selectivity in potassium channels. J Membr Biol. 1983 71(1-2):11-30. p.11 right column 2nd paragraphPubMed ID6300405 |
| Primary Source | Frankenhaeuser B, Moore LE. The effect of temperature on the sodium and potassium permeability changes in myelinated nerve fibers of Xenopus laevis. J Physiol. 1963 Nov169: 431-7.PubMed ID14079679 |
| Comments | "...channels are unusual enzymes because of the extremely high absolute rates of catalysis they bring about, 10^6-10^9 ions transported per second, orders of magnitude higher than any other turnover rates known in biochemistry. Furthermore, the temperature dependence of these rates is generally very low (Q10~1.2-1.4, or 12-25 kJ/mol activation energy) [primary source]" |
| Entered by | Uri M |
| ID | 109164 |