Temperature dependence (Q10) of transport by ion channels

Range ~1.2 to 1.4 Unitless
Organism Generic
Reference Latorre R, Miller C. Conduction and selectivity in potassium channels. J Membr Biol. 1983 71(1-2):11-30. p.11 right column 2nd paragraphPubMed ID6300405
Primary Source Frankenhaeuser B, Moore LE. The effect of temperature on the sodium and potassium permeability changes in myelinated nerve fibers of Xenopus laevis. J Physiol. 1963 Nov169: 431-7.PubMed ID14079679
Comments "...channels are unusual enzymes because of the extremely high absolute rates of catalysis they bring about, 10^6-10^9 ions transported per second, orders of magnitude higher than any other turnover rates known in biochemistry. Furthermore, the temperature dependence of these rates is generally very low (Q10~1.2-1.4, or 12-25 kJ/mol activation energy) [primary source]"
Entered by Uri M
ID 109163