Range: ±0.1 kcal/mol
||McGuffee SR, Elcock AH. Diffusion, crowding & protein stability in a dynamic molecular model of the bacterial cytoplasm. PLoS Comput Biol. 2010 Mar 5 6(3):e1000694. p.7 left column 2nd paragraphPubMed ID20221255
||"...the differences between the folding free energies in vivo
and in vitro are computed to be ... +2.2±0.1 kcal/mol
for...CRABP... (blue bars in Figure 4A), with
the positive signs indicating that the folding free energies of ...
protein are calculated to be more favorable in vivo than in vitro."