| Range |
~30 nM
|
| Organism |
Budding yeast Saccharomyces cerevisiae |
| Reference |
Varga V, Leduc C, Bormuth V, Diez S, Howard J. Kinesin-8 motors act cooperatively to mediate length-dependent microtubule depolymerization. Cell. 2009 Sep 18 138(6):1174-83. p.1180 right column 2nd paragraphPubMed ID19766569
|
| Primary Source |
Ghaemmaghami S, Huh WK, Bower K, Howson RW, Belle A, Dephoure N, O'Shea EK, Weissman JS. Global analysis of protein expression in yeast. Nature. 2003 Oct 16 425(6959):737-41.PubMed ID14562106
|
| Method |
(primary source abstract:) Researchers created a Saccharomyces cerevisiae fusion library where each open reading frame is tagged with a high-affinity epitope and expressed from its natural chromosomal location. |
| Comments |
The concentration of Kip3p in vivo is ~30 nM (700 molecules
[Ghaemmaghami et al., 2003] in a volume of 20 to 40 µm^3 [Tyson
et al., 1979]), though some molecules may not be active cellular
microtubules are up to several microns long. |
| Entered by |
Uri M |
| ID |
108078 |