Distance taken by each head taking alternating steps in kinesin

Value 16 nm
Organism Eukaryotes
Reference Gennerich A, Vale RD. Walking the walk: how kinesin and dynein coordinate their steps. Curr Opin Cell Biol. 2009 Feb21(1):59-67. doi: 10.1016/j.ceb.2008.12.002. p.59 right column bottom paragraphPubMed ID19179063
Primary Source A. Yildiz, M. Tomishige, R.D. Vale, P.R. Selvin Kinesin walks hand-over-hand Science, 303 (2004), pp. 676–678PubMed ID14684828
Comments P.59 right column bottom paragraph:"Kinesin walks in a ‘hand-over-hand’ manner [e.g. [ref 10]], with each head taking alternating 16 nm ‘steps’ (Figure 2a) [primary source]. This mechanism requires tight coupling between the biochemical cycles of both heads so that the front head remains bound to the MT [microtubule] while the rear head detaches. A conformational change in the front head then moves the detached head forward. This conformational change most probably occurs in a ∼13 aa peptide that links the motor domain to the coiled-coil stalk called the neck linker (Figure 1a) [ref 21]."
Entered by Uri M
ID 112203