mRNA transcript half life in hepatocellular carcinoma cell line HepG2 and the primary fibroblast cell line Bud8
Value | 10 Hours |
---|---|
Organism | Human Homo sapiens |
Reference | Yang E, van Nimwegen E, Zavolan M, Rajewsky N, Schroeder M, Magnasco M, Darnell JE Jr. Decay rates of human mRNAs: correlation with functional characteristics and sequence attributes. Genome Res. 2003 Aug13(8):1863-72. doi:10.1101/gr.1272403 p.1864 left column 2nd paragraphPubMed ID12902380 |
Method | To study the rates of mRNA degradation (“decay”) in human cells, researchers measured changes in mRNA levels following application of the RNA polymerase inhibitor Actinomycin D with Affymetrix U95Av2 high-density oligonucleotide arrays. |
Entered by | Uri M |
ID | 106867 |