Half-life of mouse ornithine decarboxylase (MODC)

Value ~30 min
Organism Mouse Mus musculus
Reference Li X, Zhao X, Fang Y, Jiang X, Duong T, Fan C, Huang CC, Kain SR. Generation of destabilized green fluorescent protein as a transcription reporter. J Biol Chem. 1998 Dec 25 273(52):34970-5.PubMed ID9857028
Comments A few proteins do not require ubiquitin modification for degradation. One such protein is mouse ornithine decarboxylase (MODC). MODC is the key enzyme in the biosynthesis of polyamines. This protein is known to be one of the most short lived proteins in mammalian cells, and its half-life is approximately 30 min.
Entered by Uri M
ID 105233