Half-life of photosystem protein D1

Range 19 min
Organism Cyanobacteria Synechocystis PCC 6803
Reference Moran MA et al., Sizing up metatranscriptomics. ISME J. 2013 Feb7(2):237-43. doi: 10.1038/ismej.2012.94. p.241 left column top paragraphPubMed ID22931831
Primary Source Tyystjärvi T, Aro EM, Jansson C, Mäenpää.. (1994). Changes of amino acid sequence in PEST-like area and QEEET motif affect degradation rate of D1 polypeptide in photosystem II. Plant Mol Biol 25: 517–526.PubMed ID8049374
Method Primary source abstract:"Mutations were introduced into a putative cleavage area of the D1 polypeptide (QEEET motif) and into the PEST-like area."
Comments p.240 right column bottom paragraph to p.241 left column top paragraph:"This mismatch between mRNA and protein dynamics can be partially ameliorated by targeted protein degradation when an environmental signal dissipates, or by proteins with an atypically short half-life (for example, 1 h for AraC in E. coli [BNID 105138] or 19 min for photosystem protein D1 in Synechocystis PCC 6803, Primary Source). Nonetheless, the conditions under which mRNA abundance is a strict proxy for protein abundance in a dynamic ocean may be rare for regulated genes (Figure 3)."
Entered by Uri M
ID 111931