Distance of Hepatitis-B Virus Core Capsid from central axis of HeLa cell NPC to which it binds

Value 44 nm Range: ±9 nm
Organism Human Homo sapiens
Reference Lill Y, Lill MA, Fahrenkrog B, Schwarz-Herion K, Paulillo S, Aebi U, Hecht B. Single hepatitis-B virus core capsid binding to individual nuclear pore complexes in Hela cells. Biophys J. 2006 Oct 15 91(8):3123-30PubMed ID16877503
Method Single-capsid-tracking experiments using fast wide-field fluorescence microscopy at 50 frames/s allowed researchers to directly observe specific binding via a dual-color colocalization of capsids and NPCs.
Comments NPC=nuclear pore complex
Entered by Uri M
ID 104710