| Value |
50
nM
|
| Organism |
Bacteria Escherichia coli |
| Reference |
Bintu L, Buchler NE, Garcia HG, Gerland U, Hwa T, Kondev J, Kuhlman T, Phillips R. Transcriptional regulation by the numbers: applications. Curr Opin Genet Dev. 2005 Apr15(2):125-35PubMed ID15797195
|
| Primary Source |
Oehler S, Amouyal M, Kolkhof P, von Wilcken-Bergmann B, Müller-Hill B. Quality and position of the three lac operators of E. coli define efficiency of repression. EMBO J. 1994 Jul 15 13(14):3348-55PubMed ID8045263
|
| Method |
Researchers investigated cooperative repression of the Escherichia coli lac operon by systematic conversion of its three natural operators (O1, O2 and O3) on the chromosome. |
| Comments |
This concentration corresponds to ~50 repressors per cell (BNID 102 068). 20 monomers per lacI gene given in Elf et al, 2007, PMID 17525339. For concentration of 10 nM see BNID 102083. |
| Entered by |
Uri M |
| ID |
103602 |