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Area on lipid bilayer occupied by a single alpha helix

Value	150 Å^2
Organism	Rat Rattus norvegicus
Reference	Takamori S et al., Molecular anatomy of a trafficking organelle. Cell. 2006 Nov 17 127(4):831-46. DOI: 10.1016/j.cell.2006.10.030 p.839 right column top paragraphPubMed ID17110340
Comments	P.839 right column top paragraph: "Considering that a single α helix in a membrane occupies approximately 150 Å^2 (1.5 nm^2, as estimated from the three-dimensional structures of the helical membrane proteins aquaporin-1 and the ClC chloride channel), the space requirement of all 600 transmembrane domains (if densely packed and oriented perpendicular to the membrane) amounts to 900 nm^2, i.e., 18% of the outer and 25% of the inner membrane surface."
Entered by	Uri M
ID	102782