Duration of cell cycle and S phase in proliferating thymocytes in young adult mouse

Range cell cycle ~9hours: S phase 6-7hours: G1, G2 + M very short hours
Organism Mouse Mus musculus
Reference Penit C. In vivo thymocyte maturation. BUdR labeling of cycling thymocytes and phenotypic analysis of their progeny support the single lineage model. J Immunol. 1986 Oct 1 137(7):2115-21. p.2115 left column bottom paragraphPubMed ID3093565
Primary Source [1] Bryant BJ. Renewal and fate in the mammalian thymus: mechanisms and inferences of thymocytokinetics. Eur J Immunol. 1972 Feb2(1):38-45. DOI: 10.1002/eji.1830020109PubMed ID4673318
Comments P.2115 left column bottom paragraph: "In the young adult mouse, 10 to 20% of total thymocytes are proliferating (BNID 113434). These thymic blasts are mainly located in the cortex and have a particularly high frequency in the outer subcapsular region. The entire cycle lasts about 9 hr, with a 6- to 7-hr S phase and very short G1 and G2 + M phases (primary source)."
Entered by Uri M
ID 113435