Average duration of embryonic stem (ES) cell cycle

Value 12 hours
Organism Mouse Mus musculus
Reference Festuccia N, Gonzalez I, Navarro P. The Epigenetic Paradox of Pluripotent ES Cells. J Mol Biol. 2016 Dec 15. pii: S0022-2836(16)30538-1. doi: 10.1016/j.jmb.2016.12.009. p.3 right column bottom paragraphPubMed ID27988225
Primary Source [19] P. Savatier, S. Huang, L. Szekely, K.G. Wiman, J. Samarut Contrasting patterns of retinoblastoma protein expression in mouse embryonic stem cells and embryonic fibroblasts Oncogene, 9 (1994), pp. 809–818PubMed ID8108123
Comments P.3 right column bottom paragraph: "The relatively fast ES cell cycle (12 h in average Fig. 2) is characterised by the absence of a G1/S checkpoint leading to a very short G1 and the consequent large prevalence of actively replicating cells in regular ES cultures [primary source]."
Entered by Uri M
ID 113093