Diffusion coefficient of hOgg1 DNA binding protein on elongated DNA

Range 5.78х10^5 Table - link nm^2/sec
Organism Human Homo sapiens
Reference DeSantis MC, Li JL, Wang YM. Protein sliding and hopping kinetics on DNA. Phys Rev E Stat Nonlin Soft Matter Phys. 2011 Feb83(2 Pt 1):021907 p.3 table 1PubMed ID21405863
Primary Source Blainey PC, van Oijen AM, Banerjee A, Verdine GL, Xie XS. A base-excision DNA-repair protein finds intrahelical lesion bases by fast sliding in contact with DNA. Proc Natl Acad Sci U S A. 2006 Apr 11 103(15):5752-7PubMed ID16585517
Method High-speed imaging of single hOgg1 enzyme molecules diffusing along DNA stretched by shear flow.
Comments Value given in primary source is 5?10^6bp^2/sec
Entered by Uri M
ID 107461