Effective associaton coefficient of myristoylated protein with membrane lipids

Value 10000 M^-1
Organism Generic
Reference McLaughlin S, Aderem A. The myristoyl-electrostatic switch: a modulator of reversible protein-membrane interactions. Trends Biochem Sci. 1995 Jul20(7):272-6. p.273 left column top paragraphPubMed ID7667880
Comments A ?GU of -8 kcal/mol corresponds to a partition coefficient, or effective association constant with lipids Of KA=10^4 M^-1. In other words, half of the myristoylated peptide is bound when the concentration of lipids accessible to the peptide is 10^-4M=1/kA.
Entered by Uri M
ID 105722