Apparent dissociaton constant of myristoylated protein with (2:1 PtdCho :PtdSer) vesicles

Value 6E-07 M
Organism Generic
Reference Sigal CT, Zhou W, Buser CA, McLaughlin S, Resh MD. Amino-terminal basic residues of Src mediate membrane binding through electrostatic interaction with acidic phospholipids. Proc Natl Acad Sci U S A. 1994 Dec 6 91(25):12253-7PubMed ID7527558
Method Researchers examined the contribution of electrostatic interactions to the membrane binding of Src by measuring the association of radiolabeled c-Src to LUVs (large unilamellar vesicles) composed of either electrically neutral (PC) or neutral plus acidic (2:1 PC/PS) phospholipids.
Comments See BNID 105722
Entered by Uri M
ID 105727