Number of FtsZ and UgtP (effector) molecules per cell

Range FtsZ ~5000: UgtP ~2400 molecules/cell
Organism Bacteria Bacillus subtilis
Reference Weart RB, Lee AH, Chien AC, Haeusser DP, Hill NS, Levin PA. A metabolic sensor governing cell size in bacteria. Cell. 2007 Jul 27 130(2):335-47 DOI: 10.1016/j.cell.2007.05.043 p.340 left column top paragraphPubMed ID17662947
Primary Source Feucht A, Lucet I, Yudkin MD, Errington J. Cytological and biochemical characterization of the FtsA cell division protein of Bacillus subtilis. Mol Microbiol. 2001 Apr40(1):115-25.PubMed ID11298280
Method P.339 right column bottom paragraph: "Quantitative immunoblotting indicated that there are ∼2400 molecules of UgtP per cell in LB (Figure S2D). FtsZ is estimated to be at a concentration of ∼5000 molecules per cell (primary source). Thus, UgtP inhibits FtsZ assembly at ratios that are consistent with physiological concentrations."
Entered by Uri M
ID 115560