| Range |
1.16 - 1.29 %/day
|
| Organism |
Rat Rattus norvegicus |
| Reference |
DeFesi CR, Astier HS, Surks MI. Kinetics of thyrotrophs and somatotrophs during development of hypothyroidism and L-triiodothyronine treatment of hypothyroid rats. Endocrinology. 1979 Apr104(4):1172-80 DOI: 10.1210/endo-104-4-1172 p.1179 left column 2nd paragraphPubMed ID436756
|
| Method |
Abstract: "Two experiments were performed to assess the kinetics of changes in somatotroph (St) and thyrotroph (Tt) populations in the rat anterior pituitary after thyroidectomy and during T3 treatment (10 µg/100 g BW) of thyroidectomized rats. St and Tt numbers were determined by a method combining cell counting and determination of DNA in dispersed cells as well as the percentage distribution of cells at the electron microscopic level." |
| Comments |
P.1179 left column 2nd paragraph: "The present studies show that the large decrease in the number of St [somatotroph] after thyroidectomy did not occur rapidly upon establishing the hypothyroid state. This change in St number seemed best described as a decrease at a constant fractional rate, between 1.16-1.29%/day in the two experiments." |
| Entered by |
Uri M |
| ID |
115301 |