| Range |
~32 min
|
| Organism |
Budding yeast Saccharomyces cerevisiae |
| Reference |
Brandon Ho et al., Comparative analysis of protein abundance studies to quantify the Saccharomyces cerevisiae proteome, bioRxiv preprint first posted online Feb. 2, 2017, doi: link p.8 left column bottom paragraph |
| Primary Source |
Geisberg et al., Global analysis of mRNA isoform half-lives reveals stabilizing and destabilizing elements in yeast. Cell. 2014 Feb 13 156(4):812-24. doi: 10.1016/j.cell.2013.12.026PubMed ID24529382
|
| Method |
Primary source abstract: "[Investigators] measured half-lives of 21,248 mRNA 3' isoforms in yeast by rapidly depleting RNA polymerase II from the nucleus and performing direct RNA sequencing throughout the decay process." |
| Comments |
P.8 left column bottom paragraph: "What could account for this apparent discrepancy? First, the half-life of a typical mRNA (~32 minutes) (primary source) is short compared to the typical protein (~43 minutes) (Belle et al. 2006 BNID 104151), and so it might be expected that mRNA levels would show a more rapid response to stress than would protein levels." |
| Entered by |
Uri M |
| ID |
114181 |