| Range |
1 to 2 Hours
|
| Organism |
Bacteria Escherichia coli |
| Reference |
Sigal A et al., Variability and memory of protein levels in human cells. Nature. 2006 Nov 30 444(7119):643-6. p.644 left column top paragraphPubMed ID17122776
|
| Primary Source |
Austin DW et al., Gene network shaping of inherent noise spectra. Nature. 2006 Feb 2 439(7076):608-11.PubMed ID16452980
|
| Method |
Researchers used a fluorescent labelling strategy known as
CD-tagging, which tags proteins at their endogenous chromosomal
locations |
| Comments |
Mixing
behaviour (Fig. 1a, middle and right) can be characterized by a typical
timescale tm, called the mixing time, after which cells lose the memory
of their previous protein state. "Recent studies using synthetic
protein expression systems in bacteria indicate that cells with high production tend to maintain this for about a cell generation,
yielding mixing times on the order of 1–2 h (primary source)" |
| Entered by |
Uri M |
| ID |
107861 |