Number of fos transcription factor molecules per cell

Value 4000 Molecules/cell Range: Table - link Molecules/cell
Organism Human Homo sapiens
Reference Mark D. Biggin, Animal Transcription Networks as Highly Connected, Quantitative Continua, Developmental cell Volume 21, Issue 4, 18 October 2011, Pages 611-626 DOI 10.1016/j.devcel.2011.09.008 p.617 table 1PubMed ID22014521
Primary Source De Togni P, Niman H, Raymond V, Sawchenko P, Verma IM. Detection of fos protein during osteogenesis by monoclonal antibodies. Mol Cell Biol. 1988 May8(5):2251-6. p.2251 left column 2nd paragraphPubMed ID3133556
Method (primary source abstract:) Researchers generated monoclonal antibodies by using a synthetic peptide corresponding to amino acid positions 4 to 17 of the human fos protein.
Comments Primary source (p.2251 left column 2nd paragraph) gives range of 3,000 to 5,000 molecules/cell. Cell is designated "NA" in table, unclear which cell this is. Primary source studied HeLa cells.
Entered by Uri M
ID 106905