Transport rates of synapsin and CamKIIa

Range 0.01 to 0.03 μm/sec
Organism Mammals
Reference Scott DA, Das U, Tang Y, Roy S. Mechanistic logic underlying the axonal transport of cytosolic proteins. Neuron. 2011 May 12 70(3):441-54. p.443 left column 3rd paragraphPubMed ID21555071
Primary Source Baitinger C, Willard M. Axonal transport of synapsin I-like proteins in rabbit retinal ganglion cells. J Neurosci. 1987 Nov7(11):3723-35 AND Lund LM, McQuarrie IG. Calcium/calmodulin-dependent protein kinase IIalpha in optic axons moves with slow axonal transport and undergoes posttranslational modification. Biochem Biophys Res Commun. 2001 Dec 21 289(5):1157-61 AND Petrucci TC, Macioce P, Paggi P. Axonal transport kinetics and posttranslational modification of synapsin I in mouse retinal ganglion cells. J Neurosci. 1991 Sep11(9):2938-46.PubMed ID3119792, 11741313, 1715393
Method In vivo radiolabeling experiments
Comments Primary sources listed above studied rabbit, rat and mouse, respectively
Entered by Uri M
ID 106708