Value |
3.1
% less biomass
Range: ±0.3 % less biomass
|
Organism |
Bacteria Escherichia coli |
Reference |
Stewart EJ, Madden R, Paul G, Taddei F. Aging and death in an organism that reproduces by morphologically symmetric division. PLoS Biol. 2005 Feb3(2):e45. p.0297 right column bottom paragraphPubMed ID15685293
|
Method |
"To determine if E. coli experiences aging related to the inheritance of the old pole, [investigators] followed individual exponentially growing cells in an automated fluorescence microscopy system through up to nine generations of growth and reproduction, measuring the physical parameters of each cell over time." |
Comments |
"To determine the longer-term effect of inheriting the old pole, [investigators] performed a second pairwise analysis, comparing the total length of offspring produced by sister cells from the fifth generation until the end of tracking (this generation was chosen as each cell has the opportunity to progress through about three divisions). As the bacteria are rod shaped, the total length of cells produced is proportional to the biomass of the offspring. The results show that old pole cells produce less offspring biomass compared to their new pole sisters (3.1±0.3% less, p<0.00001, t = 9.29, df = 1565)." |
Entered by |
Uri M |
ID |
111486 |