Percent that new pole cell is larger than old pole cell

Value 0.9 % larger Range: ±0.1 % larger
Organism Bacteria Escherichia coli
Reference Stewart EJ, Madden R, Paul G, Taddei F. Aging and death in an organism that reproduces by morphologically symmetric division. PLoS Biol. 2005 Feb3(2):e45. p.0298 right column top paragraphPubMed ID15685293
Method "To determine if E. coli experiences aging related to the inheritance of the old pole, [investigators] followed individual exponentially growing cells in an automated fluorescence microscopy system through up to nine generations of growth and reproduction, measuring the physical parameters of each cell over time."
Comments "Two factors from this same dataset demonstrate the lack of a juvenile phase in E. coli. First, comparison of the progeny cells shows that the new pole cell is slightly larger on average (0.9±0.1%: P<0.00001, t = 5.62, df = 7952) than the old pole cell (the contrary would be expected in the presence of a juvenile phase). Second, the young pole cell is marginally more likely to divide sooner than the old pole cell (in about 15% of the cases cells divide within the same 2-min time point: of those where the two cells divide in different time points, 54% of the time the new pole cell divides first [significant: p<0.00001, t = 5.02, df= 4812]), which is also not consistent with a phase where the young cell must grow or differentiate before reproduction."
Entered by Uri M
ID 111489